Align Technologyvs.Intuitive Surgical
ALGN vs ISRG · both in Medtech & devices, part of the Medicine, pharma & life science value chain: Medical equipment and devices, from surgery and cardiology to robotics.
Intuitive Surgical is about 15× larger than Align Technology by market cap; Align Technology trades at the lower P/E (24.4 vs 46.8); year to date, Align Technology leads (−10.4% vs −26.7%).
Side by side
| ALGN | ISRG | |
|---|---|---|
| Market cap | $10.1B | $147B |
| Price | $142.71 | $423.96 |
| Today | +1.2% | +2.1% |
| Return YTD | −10.4% | −26.7% |
| Return 1Y | +7.2% | −7.3% |
| Since June 26, 2026 | −20.0% | +4.8% |
| P/E | 24.4 | 46.8 |
| P/S | 2.4 | 13.3 |
| P/B | 2.4 | 8.1 |
Data as of 2026-10-09 · updates daily after U.S. close
Since June 26, 2026: the change in the closing price, from the daily closes Sectivia records itself since that date.
The two companies
Align TechnologyALGN
Invisalign clear aligners, backed by digital dental scanning.
Full ALGN profile →Intuitive SurgicalISRG
The da Vinci systems brought robot assistance to minimally invasive surgery and are used worldwide. Ion applies the same approach to lung biopsy, and instruments and servicing follow the installed base.
Full ISRG profile →More ALGN & ISRG comparisons
Other head-to-heads in the Medtech & devices segment.