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Alnylam Pharmaceuticalsvs.Amgen

ALNY vs AMGN · both in Biotech & innovation, part of the Medicine, pharma & life science value chain: Innovation-driven biotech companies focused on novel treatment modalities.

Amgen is about 7.3× larger than Alnylam Pharmaceuticals by market cap; Amgen trades at the lower P/E (25.2 vs 37.2); year to date, Amgen leads (+26.2% vs −43.5%).

Side by side

ALNYAMGN
Market cap$30B$220B
Price$232.68$414.87
Today+3.6%+1.8%
Return YTD−43.5%+26.2%
Return 1Y−50.2%+39.8%
Since June 26, 2026−20.1%+15.8%
P/E37.225.2
P/S6.35.8
P/B22.218.8

Data as of 2026-10-09 · updates daily after U.S. close

Since June 26, 2026: the change in the closing price, from the daily closes Sectivia records itself since that date.

The two companies

Alnylam PharmaceuticalsALNY

NASDAQ · USA

Turns RNA interference into drugs, mostly for rare and cardiovascular disease.

RNAi medicine
Full ALNY profile →

AmgenAMGN

NASDAQ · USA

Long-established in biotech, with oncology and haematology at the centre of the portfolio, immunology beside it and a line in bone disease. MariTide is the obesity candidate in the pipeline.

BiotechOncologyObesity exposure
Full AMGN profile →

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