Intuitive Surgicalvs.Stryker
ISRG vs SYK · both in Medtech & devices, part of the Medicine, pharma & life science value chain: Medical equipment and devices, from surgery and cardiology to robotics.
Intuitive Surgical is about 1.4× larger than Stryker by market cap; Stryker trades at the lower P/E (28.7 vs 46.8); year to date, Stryker leads (−21.2% vs −26.7%).
Side by side
| ISRG | SYK | |
|---|---|---|
| Market cap | $147B | $107B |
| Price | $423.96 | $277.33 |
| Today | +2.1% | +0.1% |
| Return YTD | −26.7% | −21.2% |
| Return 1Y | −7.3% | −26.2% |
| Since June 26, 2026 | +4.8% | −16.6% |
| P/E | 46.8 | 28.7 |
| P/S | 13.3 | 4.1 |
| P/B | 8.1 | 4.5 |
Data as of 2026-10-09 · updates daily after U.S. close
Since June 26, 2026: the change in the closing price, from the daily closes Sectivia records itself since that date.
The two companies
Intuitive SurgicalISRG
The da Vinci systems brought robot assistance to minimally invasive surgery and are used worldwide. Ion applies the same approach to lung biopsy, and instruments and servicing follow the installed base.
Full ISRG profile →StrykerSYK
Orthopaedic implants and surgical equipment, with Mako bringing robot assistance into the operating room.
Full SYK profile →More ISRG & SYK comparisons
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