Intuitive Surgicalvs.Stryker
ISRG vs SYK · both in Medtech & devices, part of the Medicine, pharma & life science value chain: Medical equipment and devices — from surgery and cardiology to robotics.
Intuitive Surgical and Stryker are similar in size by market cap; Stryker trades at the lower P/E (38.0 vs 48.4); year to date, Stryker leads (−6.2% vs −28.2%).
Side by side
| ISRG | SYK | |
|---|---|---|
| Market cap | $144B | $127B |
| Price | $406.78 | $329.78 |
| Today | −1.2% | +0.8% |
| Return YTD | −28.2% | −6.2% |
| Return 1Y | −22.7% | −16.5% |
| P/E | 48.4 | 38.0 |
| P/S | 13.6 | 5.0 |
| P/B | 8.2 | 5.5 |
Data as of 2026-07-11 · updates daily after U.S. close
The two companies
Intuitive SurgicalISRG
American pioneer in robot-assisted surgery — da Vinci systems are used for minimally invasive procedures worldwide.
Full ISRG profile →StrykerSYK
American medtech company focused on orthopaedics, surgical equipment and robot-assisted surgery (Mako).
Full SYK profile →More comparisons in Medtech & devices
See where ISRG and SYK sit in the full Medicine, pharma & life science map — every segment from suppliers to end markets.Open the Life science value chain →