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Johnson & Johnsonvs.Merck & Co.

JNJ vs MRK · both in Big pharma, part of the Medicine, pharma & life science value chain: Large, diversified pharmaceutical groups with broad portfolios across therapeutic areas.

Johnson & Johnson is about 1.8× larger than Merck & Co. by market cap; Johnson & Johnson trades at the lower P/E (29.0 vs 109.9); year to date, Merck & Co. leads (+35.7% vs +24.9%).

Side by side

JNJMRK
Market cap$610B$349B
Price$256.48$142.38
Today−0.8%−0.3%
Return YTD+24.9%+35.7%
Return 1Y+36.8%+63.0%
Since June 26, 2026+0.7%+10.7%
P/E29.0109.9
P/S6.25.2
P/B7.28.3

Data as of 2026-10-08 · updates daily after U.S. close

Since June 26, 2026: the change in the closing price, from the daily closes Sectivia records itself since that date.

The two companies

Johnson & JohnsonJNJ

NYSE · USA

Two businesses under one name: Innovative Medicine, which covers immunology and oncology drugs, and MedTech, which makes medical devices and surgical equipment.

Big pharmaMedtech exposureOncology
Full JNJ profile →

Merck & Co.MRK

NYSE · USA

Keytruda is the centre of the oncology business, which sits next to a substantial vaccines portfolio. Animal health forms a third division.

Big pharmaOncologyVaccines
Full MRK profile →

More JNJ & MRK comparisons

Other head-to-heads in the Big pharma segment.

See where JNJ and MRK sit in the full Medicine, pharma & life science map: every segment from suppliers to end markets.Open the Life science value chain →