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Johnson & Johnsonvs.Pfizer

JNJ vs PFE · both in Big pharma, part of the Medicine, pharma & life science value chain: Large, diversified pharmaceutical groups with broad portfolios across therapeutic areas.

Johnson & Johnson is about 3.9× larger than Pfizer by market cap; Johnson & Johnson trades at the lower P/E (29.0 vs 36.3); year to date, Johnson & Johnson leads (+24.9% vs +12.4%).

Side by side

JNJPFE
Market cap$610B$157B
Price$256.48$27.82
Today−0.8%−0.6%
Return YTD+24.9%+12.4%
Return 1Y+36.8%+6.6%
Since June 26, 2026+0.7%+14.5%
P/E29.036.3
P/S6.22.5
P/B7.21.8

Data as of 2026-10-08 · updates daily after U.S. close

Since June 26, 2026: the change in the closing price, from the daily closes Sectivia records itself since that date.

The two companies

Johnson & JohnsonJNJ

NYSE · USA

Two businesses under one name: Innovative Medicine, which covers immunology and oncology drugs, and MedTech, which makes medical devices and surgical equipment.

Big pharmaMedtech exposureOncology
Full JNJ profile →

PfizerPFE

NYSE · USA

Vaccines are what most people associate with Pfizer. The portfolio is considerably broader: oncology is a large part of it, and internal medicine covers much of the rest.

Big pharmaOncologyVaccines
Full PFE profile →

More JNJ & PFE comparisons

Other head-to-heads in the Big pharma segment.

See where JNJ and PFE sit in the full Medicine, pharma & life science map: every segment from suppliers to end markets.Open the Life science value chain →